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CASE REPORT
Year : 2021  |  Volume : 17  |  Issue : 1  |  Page : 21-24

Cerebral venous sinus thrombosis as an uncommon presentation of polycythemia vera


1 Department of General Medicine, Command Hospital (Western Command), Panchkula, Haryana, India
2 Department of Radiology, Command Hospital (Western Command), Panchkula, Haryana, India

Correspondence Address:
Dr. Rajeev Saxena
Command Hospital (Western Command), Panchkula, Haryana
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/amjm.amjm_75_20

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Cerebral venous sinus thrombosis (CVST) accounts for <1% of all cerebrovascular accidents which were attributed to increased viscosity of blood and activation of platelet in blood vessels. Polycythemia vera (PV) increases the risk of vaso-occlusive events including CVST which may be initial unusual presentation of disease. We present a 28-year-old male patient with headache associated with nausea, vomiting, and blurring of vision. Initial clinical examination was unremarkable, and blood investigations revealed erythrocytosis and neutrophilic leukocytosis with prominent granules. Brain imaging studies were consistent of cerebral venous thrombosis with hemorrhagic transformation and perilesional edema with midline shift. He was managed by decompressive hemicraniectomy, low molecular weight heparin, central nervous system decongestants, antiepileptics, and supportive care with close monitoring. PV is a hypercoagulable state which may precipitate vascular thrombosis. CVST is rare presentation of PV. Early screening for occult prothrombotic entities with prompt management increases the patient outcome and prognosis.


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